abstract：BACKGROUND:There are limited data on the effectiveness of skin cancer prevention education and early detection programs at beaches. OBJECTIVES:We evaluate 4 strategies for addressing skin cancer prevention in beach settings. METHODS:This prospective study at 4 beaches included 4 intervention conditions: (1) education...

journal_title：Journal of the American Academy of Dermatology

authors： Emmons KM,Geller AC,Puleo E,Savadatti SS,Hu SW,Gorham S,Werchniak AE,Dana-Farber Skin Cancer Screening Group.

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Cutaneous calcification is an acquired disorder whereby insoluble, amorphous calcium salts deposit in the skin. Classically, cutaneous calcification is categorized as metastatic, dystrophic, idiopathic, or iatrogenic. OBJECTIVE:The purpose of this study was to further elucidate the underlying pathogenic mec...

journal_title：Journal of the American Academy of Dermatology

authors： Pugashetti R,Shinkai K,Ruben BS,Grossman ME,Maldonado J,Fox LP

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:The expansion of store-and-forward teledermatology into underserved regions of the world has long been hampered by the requirement for computers with Internet connectivity. To our knowledge, this study is one of the first to demonstrate the feasibility of teledermatology using newer-generation mobile telepho...

journal_title：Journal of the American Academy of Dermatology

authors： Tran K,Ayad M,Weinberg J,Cherng A,Chowdhury M,Monir S,El Hariri M,Kovarik C

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:The Melasma Area and Severity Index (MASI), the most commonly used outcome measure for melasma, has not been validated. OBJECTIVE:We sought to determine the reliability and validity of the MASI. METHODS:After standardized training, 6 raters independently rated 21 patients with mild to severe melasma once d...

journal_title：Journal of the American Academy of Dermatology

authors： Pandya AG,Hynan LS,Bhore R,Riley FC,Guevara IL,Grimes P,Nordlund JJ,Rendon M,Taylor S,Gottschalk RW,Agim NG,Ortonne JP

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Basaloid squamous cell carcinoma (BSCC), an aggressive tumor of the aerodigestive tract, was described over 20 years ago, and its defining histologic parameters remain largely unchanged. While rare reports have noted cutaneous metastatic deposition, primary tumors have not been previously described. OBJECTI...

journal_title：Journal of the American Academy of Dermatology

authors： Boyd AS,Stasko TS,Tang YW

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:In the United States, complementary and alternative medicine (CAM) is used for a variety of diseases, including those of the skin. An estimate of the prevalence of CAM use among adults with skin disease using the alternative health supplement of the 2002 National Health Interview Survey (NHIS) has been publi...

journal_title：Journal of the American Academy of Dermatology

authors： Fuhrmann T,Smith N,Tausk F

更新日期：2010-12-01 00:00:00

abstract：UNLABELLED:Cyclosporine is highly effective in the treatment of a multitude of dermatoses. Concern over its side effect profile has limited its use in dermatology. Adverse effects are, for the most part, dose dependent and related to duration of therapy. Using the recommended monitoring protocols results in a significa...

journal_title：Journal of the American Academy of Dermatology

authors： Ryan C,Amor KT,Menter A

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Mohs micrographic surgery (MMS) has a low rate of surgical site infection (SSI) without the use of prophylactic antibiotics. In the studies to date, there has been variation in the steps taken by each surgeon to prevent SSIs but in all cases sterile technique was used during wound reconstruction. OBJECTIVE:...

journal_title：Journal of the American Academy of Dermatology

authors： Rogers HD,Desciak EB,Marcus RP,Wang S,MacKay-Wiggan J,Eliezri YD

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Spindle cell melanoma (SCM) including desmoplastic melanoma (DM) is a rare variant of malignant melanoma that may present diagnostic difficulties particularly when staining with S100 is negative, weak, focal, or a combination of these. Conventional melanocytic markers in SCM are usually negative. OBJECTIVE:...

journal_title：Journal of the American Academy of Dermatology

authors： Lazova R,Tantcheva-Poor I,Sigal AC

更新日期：2010-11-01 00:00:00

abstract：:The Patient Protection and Affordable Care Act will have substantial effects on the US health care system. Physicians hold varied opinions regarding the overall merits or drawbacks of the health system reform law, but it is critical that we understand its components and the implications for our practices and our patie...

journal_title：Journal of the American Academy of Dermatology

authors： Resneck JS Jr

更新日期：2010-10-01 00:00:00

abstract：:During the past two decades, systemic μ-opioid receptor antagonists (MORA) have been used in the treatment of various forms of chronic pruritus. In a number of case reports, case series, and controlled trials, treatment with MORA has demonstrated considerable antipruritic effects. In double-blind controlled studies, s...

journal_title：Journal of the American Academy of Dermatology

authors： Phan NQ,Bernhard JD,Luger TA,Ständer S

更新日期：2010-10-01 00:00:00

abstract：:Nonmelanoma skin cancer refers to a broad class of tumors, including actinic keratosis, basal cell carcinoma, and squamous cell carcinoma, and as a group these are the most frequent cancers occurring in light skinned humans. In contrast to the rarity of amelanotic melanoma, nonmelanoma skin cancer commonly lacks pigme...

journal_title：Journal of the American Academy of Dermatology

authors： Zalaudek I,Kreusch J,Giacomel J,Ferrara G,Catricalà C,Argenziano G

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Although dermatoscopy is widely used in Europe and Australia, little is known about dermatoscopy use by US dermatologists. OBJECTIVE:We sought to estimate the prevalence of dermatoscopy use by US dermatologists and examine associations with practice characteristics. METHODS:We conducted a cross-sectional s...

journal_title：Journal of the American Academy of Dermatology

authors： Engasser HC,Warshaw EM

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Very low vitamin D levels have been noted in patients with a variety of autoimmune diseases. OBJECTIVE:To determine whether low vitamin D levels are associated with autoimmunity in the setting of vitiligo vulgaris. METHODS:A prospective cohort study was conducted on 45 consecutive patients with vitiligo vu...

journal_title：Journal of the American Academy of Dermatology

authors： Silverberg JI,Silverberg AI,Malka E,Silverberg NB

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Pneumocystis carinii pneumonia (PCP) causes morbidity and mortality in immunocompromised hosts. Data describing use of PCP prophylaxis in immunosuppressed dermatologic patients are lacking. OBJECTIVE:We sought to describe the frequency of PCP among dermatologic patients receiving immunosuppression for immun...

journal_title：Journal of the American Academy of Dermatology

authors： Gerhart JL,Kalaaji AN

更新日期：2010-06-01 00:00:00

abstract：UNLABELLED:Sentinel lymph node biopsy for melanoma was introduced in the early 1990s as a minimally invasive method of identifying and pathologically staging regional lymph node basins in patients with clinical stage I/II melanoma. Numerous large trials have demonstrated that sentinel lymph node evaluation has utility ...

journal_title：Journal of the American Academy of Dermatology

authors： Stebbins WG,Garibyan L,Sober AJ

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Epidemiology and patterns of antibiotic resistance for Staphylococcus aureus are changing in the United States. OBJECTIVE:We sought to determine the epidemiology and antibiotic susceptibility profiles in S aureus cutaneous infections in a pediatric dermatology tertiary health care facility in North Carolina...

journal_title：Journal of the American Academy of Dermatology

authors： Ortega-Loayza AG,Diamantis SA,Gilligan P,Morrell DS

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Darier disease (DD) is an autosomal dominant genodermatosis caused by mutations in the ATP2A2 gene. It has been reported that depletion of Ca(2+) stores within the endoplasmic reticulum of keratinocytes is associated with impaired cell cycle regulation and terminal differentiation. Mechanical stress, heat, o...

journal_title：Journal of the American Academy of Dermatology

authors： Godic A,Korosec B,Miljković J,Kansky A,Glavac D

更新日期：2010-05-01 00:00:00

abstract：:Pyoderma gangrenosum is a rare and often painful skin disease that can be unpredictable in its response to treatment. There is currently no gold standard of treatment or published algorithm for choice of therapy. The majority of data comes from case studies that lack a standard protocol not only for treatment administ...

journal_title：Journal of the American Academy of Dermatology

authors： Miller J,Yentzer BA,Clark A,Jorizzo JL,Feldman SR

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Interferon-alfa (IFN-alpha) has been implicated in the pathogenesis of psoriasis. OBJECTIVE:To evaluate the safety profile of MEDI-545, a fully human anti-IFN-alpha monoclonal antibody and to explore its effect on the involvement of type I IFN-alpha activity in the maintenance of established plaque psoriasi...

journal_title：Journal of the American Academy of Dermatology

authors： Bissonnette R,Papp K,Maari C,Yao Y,Robbie G,White WI,Le C,White B

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Trichoadenoma is a rare benign follicular tumor first described by Nikolowski 50 years ago. Both trichoadenoma and desmoplastic trichoepithelioma are composed of cords of epithelial cells and cornifying cysts embedded in sclerotic stroma. In trichoadenoma the cystic component predominates, while desmoplastic...

journal_title：Journal of the American Academy of Dermatology

authors： Shimanovich I,Krahl D,Rose C

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Recent developments in molecular genetics may lead to re-examination of the histopathology of inherited palmoplantar keratodermas (PPKs) based on more precise groupings of the various entities and syndromes. OBJECTIVE:We sought to characterize the histopathological findings in PPKs associated with mutations...

journal_title：Journal of the American Academy of Dermatology

authors： Bergman R,Hershkovitz D,Fuchs D,Indelman M,Gadot Y,Sprecher E

更新日期：2010-01-01 00:00:00

abstract：:In autosomal dominant skin disorders, a pronounced mosaic involvement may sometimes be found to be superimposed on the ordinary nonsegmental lesions. Such "type 2 segmental manifestation" reflects loss of heterozygosity occurring at an early developmental stage, giving rise to a cell clone that lacks the corresponding...

journal_title：Journal of the American Academy of Dermatology

authors： Happle R

更新日期：2010-01-01 00:00:00

abstract：:Psoriasis is a common, chronic, inflammatory, multisystem disease with predominantly skin and joint manifestations affecting approximately 2% of the population. In this fifth of 6 sections of the guidelines of care for psoriasis, we discuss the use of ultraviolet (UV) light therapy for the treatment of patients with p...

journal_title：Journal of the American Academy of Dermatology

authors： Menter A,Korman NJ,Elmets CA,Feldman SR,Gelfand JM,Gordon KB,Gottlieb A,Koo JYM,Lebwohl M,Lim HW,Van Voorhees AS,Beutner KR,Bhushan R

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Nephrogenic systemic fibrosis is a fibrosing disorder associated with gadolinium (Gd)-based contrast agents dosed during renal insufficiency. OBJECTIVE:In two patients, Gd deposition in tissue affected by nephrogenic systemic fibrosis was quantified using inductively coupled plasma mass spectrometry. The pr...

journal_title：Journal of the American Academy of Dermatology

authors： High WA,Ranville JF,Brown M,Punshon T,Lanzirotti A,Jackson BP

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Orthopedic surgical procedures involving the foot and ankle are associated with high rates of infection. The optimal method of preparing the skin and nails for foot and ankle surgery remains unknown. OBJECTIVE:This study was conducted to compare the efficacy of 4 different methods of skin and nail preparati...

journal_title：Journal of the American Academy of Dermatology

authors： Becerro de Bengoa Vallejo R,Losa Iglesias ME,Alou Cervera L,Sevillano Fernández D,Prieto Prieto J

更新日期：2009-12-01 00:00:00

abstract：:Dialogues in Dermatology, a monthly audio program from the American Academy of Dermatology, contains discussions between dermatologists on timely topics. Commentaries from Dialogues Editor-in-Chief Jacqueline M. Junkins-Hopkins, MD, are provided after each discussion as a topic summary and are provided here as a speci...

journal_title：Journal of the American Academy of Dermatology

authors： Junkins-Hopkins JM

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Lymphomatoid papulosis (LyP) is a cyclic papulonodular eruption that is clinically benign and histologically malignant. Association with hematologic neoplasias has been reported in 5% to 20% of all cases. OBJECTIVE:We sought to review the clinical and histopathologic features of LyP in pediatric patients. ...

journal_title：Journal of the American Academy of Dermatology

authors： de Souza A,Camilleri MJ,Wada DA,Appert DL,Gibson LE,el-Azhary RA

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Psoralen plus ultraviolet A (PUVA) for the treatment of psoriasis has never been evaluated using the Psoriasis Area Severity Index (PASI) in a randomized, double-blind, placebo-controlled trial. The lack of such data limits our capacity to estimate PUVA's efficacy relative to other treatment options that are...

journal_title：Journal of the American Academy of Dermatology

authors： Sivanesan SP,Gattu S,Hong J,Chavez-Frazier A,Bandow GD,Malick F,Kricorian G,Koo J

更新日期：2009-11-01 00:00:00

abstract：:Given the increasing incidence and prevalence of skin cancer, dermatologists are more frequently recommending sunscreens to their patients. However, the safety of titanium dioxide and zinc oxide nanosized particles in the majority of sunscreens has come under scrutiny from governments and the general public. We sought...

journal_title：Journal of the American Academy of Dermatology

authors： Newman MD,Stotland M,Ellis JI

更新日期：2009-10-01 00:00:00

abstract：:Sebaceous lesions are associated with two syndromes with widespread multisystem disorders and tumors. Linear sebaceous nevus syndrome has been traditionally known as the triad of sebaceous nevus of Jadassohn, seizures, and mental retardation. This syndrome encompasses a much broader spectrum of multisystem disorders, ...

journal_title：Journal of the American Academy of Dermatology

authors： Eisen DB,Michael DJ

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Psychogenic excoriation describes patients who excoriate without apparent primary skin abnormality. OBJECTIVE:This study compares the psychiatric profile of patients with psychogenic excoriation with a control group. METHODS:Fifty consecutive patients with psychogenic excoriation were matched with 50 contr...

journal_title：Journal of the American Academy of Dermatology

authors： Mutasim DF,Adams BB

更新日期：2009-10-01 00:00:00

abstract：:Based upon case reports and small case series, it has been known for many years that some types and subtypes of inherited epidermolysis bullosa (EB) may be at risk for developing one or more extracutaneous complications. Many of these are associated with considerable morbidity; some may result in death. Only over the ...

journal_title：Journal of the American Academy of Dermatology

authors： Fine JD,Mellerio JE

更新日期：2009-09-01 00:00:00

abstract：:Two patients with atypical histologic and immunohistochemical findings in nevi after cryotherapy are reported. Patient 1, a 32-year-old white woman, presented to our cancer center with two changing moles that had been treated with liquid nitrogen therapy by her primary care provider. After cryotherapy, these two lesio...

journal_title：Journal of the American Academy of Dermatology

authors： Adeniran AJ,Prieto VG,Chon S,Duvic M,Diwan AH

更新日期：2009-08-01 00:00:00

abstract：:Pityriasis rosea is an acute, self-healing exanthem characterized by oval erythematous-squamous lesions of the trunk and limbs, that usually spares face, scalp, palms, and soles. Constitutional symptoms, which have the character of true prodromes; clinical features, which resemble those of the known exanthems; and man...

journal_title：Journal of the American Academy of Dermatology

authors： Drago F,Broccolo F,Rebora A

更新日期：2009-08-01 00:00:00

abstract：:Clinical trials for systemic psoriasis therapy typically enroll healthy patients and exclude patients with cardiovascular disease, latent tuberculosis, liver disease, histories of malignancies, viral infections, children, and pregnant or breast-feeding women. Physicians often require guidance for optimum management of...

journal_title：Journal of the American Academy of Dermatology

authors： Strober B,Berger E,Cather J,Cohen D,Crowley JJ,Gordon KB,Gottlieb A,Horn EJ,Kavanaugh AF,Korman NJ,Krueger GG,Leonardi CL,Menter A,Schwartzman S,Sobell JM,Young M

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Carney complex (CNC) is an autosomal dominant disorder associated with multiple neoplasms. OBJECTIVE:We report a case of a 40-year-old Caucasian man with a sporadic form of CNC. METHODS:This is a clinicopathologic description and molecular biological study with an emphasis on histopathologic findings. RES...

journal_title：Journal of the American Academy of Dermatology

authors： Kacerovska D,Sima R,Michal M,Hes O,Roucka P,Zarybnicka M,Hora M,Chudacek Z,Kazakov DV

更新日期：2009-07-01 00:00:00

abstract：:We discuss a metastatic dermatofibrosarcoma protuberans on the occiput of a 53-year-old man whose initial tumor appeared on his forehead 23 years previously. The pathology of the tumor that recurred at the initial site was fibrosarcomatous dermatofibrosarcoma protuberans, whereas the metastatic tumor was a pigmented d...

journal_title：Journal of the American Academy of Dermatology

authors： Kabumoto T,Fujiwara H,Kariya N,Tsujimoto T,Ito K,Ito M,Kobayashi H

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Dermatopathologists often are asked by clinicians to report margins on punch excisions of melanocytic lesions. OBJECTIVE:We sought to determine the adequacy of surgical margins on melanocytic lesions submitted with intention of complete excision using punch removal technique. METHODS:We conducted prospecti...

journal_title：Journal of the American Academy of Dermatology

authors： Chang TT,Somach SC,Wagamon K,Somani AK,Pomeranz J,Jaworsky C,Bass J,Winfield HL,Sigel JE,Rosenberg AS

更新日期：2009-06-01 00:00:00

abstract：:We describe asymptomatic bone cysts in the right humerus of a 17-year-old boy with Darier disease. The cysts were found when a radiographic skeletal survey was performed to monitor for adverse effects of oral retinoid therapy. Magnetic resonance imaging was used to confirm that the lesions were cystic and to delineate...

journal_title：Journal of the American Academy of Dermatology

authors： Ramien ML,Prendiville JS,Brown KL,Cairns RA

更新日期：2009-06-01 00:00:00